Peperomia pellucida, a tropical herb in the Piperaceae family, has long served traditional medicinal roles in regions such as Indonesia, Nigeria, the Philippines, Brazil, and India.
Commonly regarded as a weed, it has nonetheless featured in folk medicine for treating fever, headache, gout, hypertension, and wounds.
Phytochemical analyses have revealed a broad spectrum of bioactive substances—tannins, saponins, phenolics, flavonoids, alkaloids, essential oils, terpenoids, fatty acids, steroids, and amino acids.
These compounds are thought to contribute to the plant's effects on inflammation, analgesia, microbial infections, oxidative stress, hyperglycemia, hypertension, gout, and gastrointestinal protection.
Peperomia pellucida activity profiles show consistent antihypertensive, anti-inflammatory, antipyretic, analgesic, antiplasmodial, antimicrobial, antidiarrheal, osteogenic, gastroprotective, and antioxidant effects.
Ahmad, I., Hikmawan, B. D., Sulistyarini, R., & Mun’im, A. (2023). Peperomia pellucida (L.) Kunth herbs: A comprehensive review on phytochemical, pharmacological, extraction engineering development, and economic promising perspectives. Journal of Applied Pharmaceutical Science, 13(01), 001–009. https://doi.org/10.7324/JAPS.2023.130201
Alves, N. S. F., Setzer, W. N., & da Silva, J. K. R. (2019). The chemistry and biological activities of Peperomia pellucida(Piperaceae): A critical review. Journal of Ethnopharmacology, 232, 90–102. https://doi.org/10.1016/j.jep.2018.12.021
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